Associate Professor, M.D., Ph.D., FAAP
Yelizaveta Konnikova
Associate Professor in Pediatrics with secondary appointments in Immunobiology and Obstetrics, Gynecology, and Reproductive Sciences
CyTOF Core Director, Medicine
Yale University, New Haven, CT, USA
ORCID
Short CV
Liza Konnikova is Associate Professor in Pediatrics at Yale University with secondary appointments in Immunobiology and Obstetrics, Gynecology, and Reproductive Sciences.
Education/Training
Brandeis University, BA 06/1999 Biology and Chemistry; Tufts University School of Medicine MD, PhD 05/2007 Medicine, Physiology; Boston Combined Residency Program Internship 06/2008 Pediatrics; Boston Combined Residency Program Residency 06/2010 Pediatrics; Boston Children's Hospital, Clinical Fellowship 06/2013 Neonatology; Boston Children's Hospital, Research Fellowship 06/2017 Mucosal Immunology
Positions and Scientific Appointments
2017-2019 Assistant Professor, tenure-stream, University of Pittsburgh, Pittsburgh, MA
2020-2023 Assistant Professor, tenure stream, Yale School of Medicine, New Haven, CT
2020- Program member, Human Translational Immunology, Yale School of Medicine, New Haven, CT
2023- Program member, Center for System’s Engineering and Immunology, Yale School of Medicine,
New Haven, CT
2023- Program member, Program in Translation Biomedicine, Yale School of Medicine, New Haven, CT
2023- Associate Professor, tenure stream, Departments of Pediatrics, Immunobiology and Ob, Gyn and Reproductive Sciences, Yale School of Medicine, New Haven, CT
2023- Director of the CyTOF core, Yale University, New Haven, CT
Research Interest
Extensive expertise in mucosal immunology, translational research, tissue collection, and biobanking, systems biology approaches and cutting-edge techniques, such as imaging, suspension mass cytometry, and single-cell RNA sequencing, intestinal organoid cultures, large biobank of control and diseased cryopreserved tissue spanning the human lifespan.
Publications:
https://www.ncbi.nlm.nih.gov/myncbi/liza.konnikova.1/bibliography/public/
Lab Skill
Dr. Konnikova's team focuses on the development of early life immunity particularly at barrier sites such as the GI tract and the maternal-fetal interface with a particular focus on T cell biology. Using multi-omic approaches, the group investigates how mucosal homeostasis is developed and what contributes to pathogenesis of diverse diseases such as sepsis, preterm labor, necrotizing enterocolitis (NEC), very early onset (VEO) and pediatric IBD. The Konnikova lab is further interested in how the microbiome and the associated metabolome regulate immune development and homeostasis at barrier sites. Her group is also interested in how early life events alter circulating immune cells. To this end, in collaboration with the NOuRISH team they are enrolling infants in a longitudinal study of peripheral blood development.